The SKY results for the NCBI cases have been added, resulting in generation of composite imbalance profiles.
As a reminder: Imbalances are are generated from banding/SKY/MFISH (they are all considered the same quality) first; then, everything found in CGH is added. This seems to be reasonable, as CGH should be better for imbalances, though may miss some changes just appearing in subclones.
However, I have decided to remove the blue breakpoint-bars from the ideograms, as they tended to irritate some users. The data is still available in the downloads, though
Saturday, August 19, 2006
Thursday, August 17, 2006
14795 cases from 577publications
For the update today, I have had a look at the current state of the NCBI SKY/CGH database. I (re-) wrote a parser for their XML file format, which currently only interprets CGH annotations.
Of the 840 human CGH cases from the current NCBI Sky/CGH XML dump, about 600 were included into th edatabase from this source; the remaining cases had been collected from the literature or submitted by the authors to Progenetix.
For cases with both SKY and CGH data, the MFISH/SKY information will be added later.
Of the 840 human CGH cases from the current NCBI Sky/CGH XML dump, about 600 were included into th edatabase from this source; the remaining cases had been collected from the literature or submitted by the authors to Progenetix.
For cases with both SKY and CGH data, the MFISH/SKY information will be added later.
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