Thanks to a review of selected cases by Turid Knutsen, a number of changes have been implemented in the karyotype parser portion of the ISCN2matrix engine. This concerns mostly the handling of ambiguous annotations, but also some previous omissions of specific patterns.
The changes are active in the online parser, and will be propagated to the data set soon.
2007-12-20
2007-12-12
data review and site overhaul
The site has had a layout overhaul (the changes in code are more than skin deep, though). On the data side, the emphasis is mostly on review and adding clinical information. As a ballpark estimate, gender and age information should be available for about half the cases - but this may take some months. Even followup / survival data will become accessible for a proportion of cases. Of course, this data is dependent on the published results, and / or the willingness of the authors to dig deeply into their old lab records ...
On the minus side, the case number just dropped slightly, to now 16998. This was due to one doubled publication entry, and one pure SKY data set that was removed (still accessible through NCBI).
As general policy, metaphase banding (incl. MFISH/SKY data) is only presented if it had been directly added to Progenetix (e.g. the DSMZ cell lines, or as part of some specific data review project). Otherwise, only cases with composite analysis (e.g. CGH and banding) are kept for now.
On the minus side, the case number just dropped slightly, to now 16998. This was due to one doubled publication entry, and one pure SKY data set that was removed (still accessible through NCBI).
As general policy, metaphase banding (incl. MFISH/SKY data) is only presented if it had been directly added to Progenetix (e.g. the DSMZ cell lines, or as part of some specific data review project). Otherwise, only cases with composite analysis (e.g. CGH and banding) are kept for now.
Subscribe to:
Posts (Atom)